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Advanced Experimental Techniques In Powder Metallurgy

RRP $271.99

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The increasing use of powder metallurgy techniques to make an almost infinite variety of materials and products places greater emphasis on utilization of sophisticated experimental techniques. Usually research and development efforts initiate the use of newly developed equipment and analytical procedures. Indeed, the contents of this book are strongly linked to research endeavors, in both the academic and industrials worlds. However, this volume can serve a much needed function in industrial applied powder metallurgy. Although many research­ ers will find the contents of great value, the technical personnel more involved with production, quality control, customer services and product design now have at their dispo­ sal a means to learn about the potential uses of several very important techniques. With today's "knowledge explosion" the present set of papers greatly facilitates the comprehension and adoption of new procedures. If powder metallurgy is to continue its rapid rate of growth in virtually all segments of industry, then the transition of modern equipment and procedures from tools of research and development laboratories to everyday plant operations and applications must be hastened. The editors hope that this volume aids in this process, as well as assisting students and researchers by providing a ready source of up-to-date useful information.


Building A Virtual Library

RRP $244.99

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The organization, functioning, and the role of libraries in university communities continue to change dramatically. While academic research libraries continue to acquire information, organize it, make it available, and preserve it, the critical issues for their management teams in the twenty-first century are to formulate a clear mission and role for their library, particularly as libraries transition to meet the new information needs of their university constituents. Building a Virtual Library addresses these issues by providing insight into the current changes and developments within the area of library science.


Cell Death Techniques

RRP $289.99

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Regulated cell death, which is involved in nearly every aspect of animal development and physiology, can be challenging to study in the laboratory. There are multiple types of cell death, several interconnected signaling pathways can be activated, and the postmortem consequences may vary. Therefore, a combination of specialized techniques is often required to characterize and confirm cell death in the system of interest.

This laboratory manual provides a comprehensive suite of step-by-step protocols for inducing, detecting, visualizing, characterizing, and quantifying cell death in a variety of systems. The contributors describe strategies for identifying and evaluating the biochemical and morphological changes that occur during apoptosis, autophagy, necrosis, and other forms of cell death, as well as for pinpointing the genes and proteins that may be involved. The protocols employ flow cytometry, imaging and microscopy, RNAi, western blotting, enzymatic activity measurements, and other tools to assess phenomena such as DNA fragmentation, lysosomal membrane permeabilization, autophagic flux, apoptosome or ripoptosome formation, caspase activation, and cytochrome c release. Techniques are described for both in vitro systems and in vivo models, including mice, C. elegans, and Drosophila.

The authors also provide guidance on interpreting and presenting the results of cell death experiments, as well as advice on complementary procedures that may be required to confirm the results of a given experiment. This indispensable laboratory resource will enable all cell and developmental biologists, from the graduate level upward, to confidently carry out and comprehend a wide array of cell viability assays.



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